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Novel class I HDAC inhibitors that are impervious to glucuronidation for the treatment of hematologic malignancies and inflammatory diseases/disorders

Novel class I HDAC inhibitors that are impervious to glucuronidation for the treatment of hematologic malignancies and inflammatory diseases/disordersTechnology: MUSC researchers have developed a series of potent and selective class I histone deacetylase (HDAC) inhibitors that do not suffer from the genotoxicity, off-target effects, and metabolic inactivation...

Published: 2/5/2023 | Updated: 2/5/2023 | Inventor(s): Chung-Jen (James) Chou, Jesse McClure, Cheng Zhang, Elizabeth Inks

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Category(s): BioPharma